C-Reactive Protein Unit Converter

C-reactive protein (CRP) is a protein produced by the liver in response to inflammation anywhere in the body. It's one of the most sensitive acute-phase reactants, meaning it rises rapidly when inflammation occurs.

CRP levels can increase within 6-12 hours of an inflammatory stimulus and peak at 24-48 hours. In healthy adults, CRP is normally present in trace amounts (less than 5 mg/L), but during severe infections or major trauma, levels can rise to 300 mg/L or higher.

A high-sensitivity CRP (hs-CRP) test measures very low levels of CRP and is primarily used to assess cardiovascular disease risk, while a standard CRP test detects higher levels associated with infections or inflammatory conditions.

CRP is synthesized primarily by the liver in response to interleukin-6 (IL-6) and other pro-inflammatory cytokines released during inflammation, infection, or tissue injury. Adipose (fat) tissue also produces IL-6, which is why obesity is associated with elevated CRP levels.