Gamma-Glutamyl Transferase (GGT) Unit Converter

Gamma-glutamyl transferase (GGT) is an enzyme found in cell membranes throughout the body, with the highest concentrations in the liver, kidneys, and pancreas. It plays a key role in breaking down and recycling glutathione, the body's most important antioxidant.

Although GGT is present in many tissues, the enzyme measured in the blood originates primarily from the liver and bile ducts. When liver cells or bile ducts are damaged, GGT leaks into the bloodstream, causing levels to rise.

GGT is one of the most sensitive markers of liver and bile duct problems, often rising before other liver enzymes. It is commonly measured alongside alkaline phosphatase (ALP) to help distinguish between liver and bone conditions.

GGT is found in the cell membranes of the liver, kidneys, pancreas, intestine, spleen, heart, brain, and seminal vesicles. Although kidney tissue has the highest GGT activity, the enzyme measured in blood comes primarily from the liver and biliary tract.